NALT- versus PEYER'S-patch-mediated mucosal immunity
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چکیده
منابع مشابه
Mucosal immunity.
Food allergy is the manifestation of an abnormal immune response to antigen delivered by the oral route. Normal mucosal immune responses are generally associated with suppression of immunity. A normal mucosal immune response relies heavily on a number of factors: strong physical barriers, luminal digestion of potential antigens, selective antigen sampling sites, and unique T-cell subpopulations...
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Although over 90% of all human infections begin at a mucosal site (respiratory, gastrointestinal, urogenital, or ocular), the total number of infections occurring in the population is relatively low. This is in part the result of the secretion of a complex array of local and systemically produced immunoglobulins (Igs). Since the time of Pasteur (37), when immunization by the oral route was firs...
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Cellular immune responses were studied in 35 Brazilian patients with either active cutaneous leishmaniasis (CL), active mucosal leishmaniasis (ML), or healed cutaneous leishmaniasis. The mean age and duration of illness in the two groups were as follows: 14 CL patients, age 28 +/- 13 yr, disease 5 +/- mo; and 16 ML patients, age 34 +/- 15 yr, disease 86 +/- 117 mo. Patients with CL and ML respo...
متن کاملMucosal Immunity and Vaccines
These mucosal surfaces, while located inside the body, are actually a physical barrier between the outside and the sterile interior cavity of the body known as the “systemic” environment. Critical nutrients, oxygen and other molecules are constantly taken up across these mucosal barriers; however, another important function of the mucous is to keep invading pathogens out [15]. Daily these mucou...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2004
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri1439